abstract：BACKGROUND:The aim of this study was to evaluate the efficacy of lamivudine (LAM) monoprophylaxis for patients with non-replicating hepatitis B virus (HBV) infection at orthotopic liver transplantation (OLT). METHODS:Among 128 liver recipients with HBV infection between 1994 and 2004 transplanted at our institution, 6...

journal_title：Clinical transplantation

authors： Yoshida H,Kato T,Levi DM,Regev A,Madariaga JR,Nishida S,Martinez EJ,Schiff ER,Omata M,Tzakis AG

更新日期：2007-03-01 00:00:00

abstract：:Tuberculosis remains one of the most serious infections after organ transplantation. Isoniazid prophylaxis for liver transplant recipients with a history of tuberculosis is generally recommended. However, its benefit is controversial because of potential hepatotoxicity of isoniazid. It is crucial to determine appropri...

journal_title：Clinical transplantation

authors： Nagai S,Fujimoto Y,Taira K,Egawa H,Takada Y,Kiuchi T,Tanaka K

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:End-stage renal disease is associated with illness-induced disruptions that challenge patients and their families to accommodate and adapt. However, the impact of patients' marital status on kidney transplant outcome has never been studied. This project, based on data from United States Renal Data System (US...

journal_title：Clinical transplantation

authors： Naiman N,Baird BC,Isaacs RB,Koford JK,Habib AN,Wang BJ,Barenbaum LL,Goldfarb-Rumyantzev AS

更新日期：2007-01-01 00:00:00

abstract：:To examine the efficacy and safety of enteric-coated mycophenolate sodium (EC-MPS, myfortic) in renal transplant patients with diabetes mellitus, six- and 12-month data from three clinical trials with EC-MPS (Studies B301, B302, and myPROMS) were analyzed post hoc. Studies B301 (de novo patients) and B302 (maintenance...

journal_title：Clinical transplantation

authors： Pietruck F,Budde K,Salvadori M,Sollinger H,Bourbigot B,Gentil MA,Oppenheimer F

更新日期：2007-01-01 00:00:00

abstract：:The exact mechanism of acute and chronic allograft rejection still remains unclear. The chemokine SDF-1 as mediator of allograft rejection has been under intensive investigation in liver, cardiac and bone marrow transplantation, whereas in renal transplantation, there are no reports about SDF-1 to date. This study was...

journal_title：Clinical transplantation

authors： Hoffmann U,Banas B,Krüger B,Banas M,Bergler T,Böger C,Kammerl M,Obed A,Rümmele P,Segerer S,Riegger GA,Krämer BK

更新日期：2006-11-01 00:00:00

abstract：:The non-relapse mortality of autologous stem cell transplant is low enough that the procedure has been extended to older patients with non-Hodgkin's lymphoma. We treated 537 non-Hodgkin's lymphoma patients with high-dose chemotherapy consisting of busulfan, cyclophosphamide, and etoposide followed by autologous stem c...

journal_title：Clinical transplantation

authors： Kalaycio M,Pohlman B,Kuczkowski E,Rybicki L,Andresen S,Sobecks R,Bolwell B

更新日期：2006-11-01 00:00:00

abstract：:Portal vein thrombosis (PVT), a common complication of end stage liver disease, is no longer considered a definite contraindication for liver transplantation (LTx). The clinical decision to perform an LTx in the case of PVT depends on the degree of PVT and the experience of the surgeon. Eversion thromboendovenectomy w...

journal_title：Clinical transplantation

authors： Paskonis M,Jurgaitis J,Mehrabi A,Kashfi A,Fonouni H,Strupas K,Büchler MW,Kraus TW

更新日期：2006-09-01 00:00:00

abstract：:The study explores the prevalence of unrecognized diabetes mellitus (DM), the incidence and risk factors new onset diabetes mellitus (NODM) and determines whether patient survival differs between patients with transient (NODM that resolves) compared with those with fixed NODM. This is a single center review of solitar...

journal_title：Clinical transplantation

authors： Kiberd M,Panek R,Kiberd BA

更新日期：2006-09-01 00:00:00

abstract：:Tacrolimus (TAC) is a calcineurin inhibitor that is used for cardiac allograft rejection. Efficacy and safety data of a combined TAC/mycophenolate mofetil (MMF) therapy in comparison with a TAC/cortisone therapy in heart recipients are lacking. We analysed the clinical outcome of 41 patients who received TAC in combin...

journal_title：Clinical transplantation

authors： Fuchs U,Tenderich G,Zittermann A,Szabados F,Minami K,Koerfer R

更新日期：2006-07-01 00:00:00

abstract：:The effect of additional venous reconstruction on morphologic and functional regeneration of the anterior segment of right-lobe liver grafts was compared among three groups according to graft type: right liver graft without the middle hepatic vein (MHV) or MHV tributaries (n=7), with MHV tributaries (n=25) and with th...

journal_title：Clinical transplantation

authors： Mizuno S,Iida T,Yagi S,Usui M,Sakurai H,Isaji S,Uemoto S

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Renal transplantation is an excellent therapeutic alternative for end-stage renal diseases. Nevertheless, the cardiac function is often impaired in renal-transplant patients (RTR) and importantly determines their prognosis. Adrenomedullin (ADM), a peptide involved in cardiovascular homeostasis, is believed t...

journal_title：Clinical transplantation

authors： Geny B,Ellero B,Chakfé N,Kretz JG,Brandenberger G,Piquard F

更新日期：2006-05-01 00:00:00

abstract：:This study evaluated the efficacy of primary endovascular stenting in cases of transplant renal artery stenosis (TRAS) from cadaver and non-heart-beating donor kidneys. Patients with TRAS (n = 13) from a single-centre transplant population (n = 476) were treated by primary percutaneous angioplasty and endovascular ste...

journal_title：Clinical transplantation

authors： Ridgway D,White SA,Nixon M,Carr S,Blanchard K,Nicholson ML

更新日期：2006-05-01 00:00:00

abstract：:We report the case of a female with chronic pancreatitis who underwent multiple surgical procedures leading to total resection of the pancreas with successful islet auto-transplantation. Postoperatively, she developed heparin-induced thrombocytopenia. Heparinization prior to islet infusion is currently recommended to ...

journal_title：Clinical transplantation

authors： Rastellini C,Brown ML,Cicalese L

更新日期：2006-03-01 00:00:00

abstract：:Use of C(2) monitoring for cyclosporine A (CsA) microemulsion results in improved clinical outcomes vs. trough (C(0)) monitoring. Logistical issues include accurate timing of the C(2) sample; requirement for sample dilution with most standard assay techniques; and inconvenience for patients. Recently, it has been show...

journal_title：Clinical transplantation

authors： Yonan N,Martyszczuk R,Machaal A,Baynes A,Keevil BG

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Although innate immunity is crucial to host defense against pathogens, the extent to which innate immune mechanisms participate in the rejection of allogenic tissues in humans is unknown. We hypothesize that activation of innate immunity through Toll-like receptors (TLRs) critically regulates the development...

journal_title：Clinical transplantation

authors： Palmer SM,Burch LH,Mir S,Smith SR,Kuo PC,Herczyk WF,Reinsmoen NL,Schwartz DA

更新日期：2006-01-01 00:00:00

abstract：:A better understanding of the immunobiological processes and predictors of graft rejection holds promise for the development of potential therapeutic strategies and also individualization of immunosuppression. The objective of this study is to analyze the clinical relevance of immune parameters such as antidonor antih...

journal_title：Clinical transplantation

authors： Panigrahi A,Deka R,Bhowmik D,Dash SC,Tiwari SC,Guleria S,Mehta SN,Mehra NK

更新日期：2006-01-01 00:00:00

abstract：:Ten-year protocol biopsies were performed in 16 patients treated with calcineurin inhibitor (CNI) continuously. All kidney grafts were functioning well at the time of biopsy with the mean serum creatinine level of 1.6 +/- 0.8 mg/dL. The specimen of biopsy showed various degrees of tissue injury. According to the Banff...

journal_title：Clinical transplantation

authors： Okamoto M,Akioka K,Ushigome H,Higuchi A,Nobori S,Ogino S,Uryuhara K,Kaihara S,Hatta T,Urasaki K,Yoshimura N

更新日期：2006-01-01 00:00:00

abstract：:Simultaneous pancreas-kidney transplantation is an established procedure for patients with type I diabetes and end-stage renal disease. Continuous advances in the operation techniques with consequent reduction of perioperative morbidity and mortality and the introduction of modern immunosuppressive agents improved not...

journal_title：Clinical transplantation

authors： Schmied BM,Müller SA,Mehrabi A,Welsch T,Büchler MW,Zeier M,Schmidt J

更新日期：2006-01-01 00:00:00

abstract：:Liver transplantation for hepatitis B virus (HBV)-related liver disease has changed from a contraindication to outcomes comparable with non-HBV-related liver transplantations during the last two decades. Mainly the implementation of immunoprophylaxis with hepatitis B immunoglobulin (HBIG) and the use of nucleoside ana...

journal_title：Clinical transplantation

authors： Eisenbach C,Sauer P,Mehrabi A,Stremmel W,Encke J

更新日期：2006-01-01 00:00:00

abstract：:Human parvovirus B19 (B19) infection has been known to cause chronic anemia, pure red cell aplasia (PRCA), glomerulopathy, and allograft dysfunction in kidney transplant (KT) recipients. The aim of this study was to evaluate the incidence and clinical significance of B19 infection in KT recipients. A total of 537 seru...

journal_title：Clinical transplantation

authors： Ki CS,Kim IS,Kim JW,Lee NY,Kim SH,Lee KW,Kim SJ,Joh JW,Huh WS,Oh HY

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Chronic allograft nephropathy (CAN), associated with late-allograft dysfunction is caused by alloantigen-dependent and -independent mechanisms, and eventually leads to interstitial fibrosis (ci). Activation of complement cascade is considered to be a poor prognostic marker of graft survival. This study was d...

journal_title：Clinical transplantation

authors： Ohba K,Miyata Y,Koga S,Nishikido M,Kanetake H,Nazneen A,Razzaque MS,Taguchi T

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:The role of advanced age live donors remains controversial because of decline in glomerular filtration rate and perceived increased risks of perioperative complications. METHODS:A retrospective review of all live donor transplants performed from January 2000 to December 2003. RESULTS:Seventy-eight live don...

journal_title：Clinical transplantation

authors： Johnson SR,Khwaja K,Pavlakis M,Monaco AP,Hanto DW

更新日期：2005-10-01 00:00:00

abstract：:The development of post-transplant lymphoproliferative disorders (PTLD) is a well-recognized complication of solid organ transplantation in patients receiving immunosuppressive therapy. The literature on PTLD in live renal allograft recipients is scarce and most of the data pertains to PTLD in cadaveric transplants. A...

journal_title：Clinical transplantation

authors： Jain M,Badwal S,Pandey R,Srivastava A,Sharma RK,Gupta RK

更新日期：2005-10-01 00:00:00

abstract：:Experimental models suggest that endothelin-1 (ET-1) has a significant role in the pathogenesis of cyclosporin A (CyA)-induced hypertension. However, its serum levels evaluated in different studies, including patients who received solid organ transplants, exhibited controversial results. Our study population consisted...

journal_title：Clinical transplantation

authors： Cauduro RL,Costa C,Lhulier F,Garcia RG,Cabral RD,Gonçalves LF,Manfro RC

更新日期：2005-08-01 00:00:00

abstract：:Early steroid discontinuation (ESD) has been associated with a lower incidence of post-transplant diabetes mellitus (PTDM). We retrospectively reviewed the incidence of PTDM in relation to racial groups in kidney transplant recipients treated with ESD. Between January 2002 and September 2003, 125 consecutive primary a...

journal_title：Clinical transplantation

authors： Walczak DA,Calvert D,Jarzembowski TM,Testa G,Sankary HN,Thielke J,Oberholzer J,Benedetti E

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:With the aim to improve the inferior outcomes in elderly recipients of kidneys from elderly cadaver donors, we applied and investigated a therapeutic regimen consisting of calcineurin inhibitor (CNI)-free, mycophenolate mofetil (MMF)-based immunosuppressive (i.s.) induction/maintenance protocol. In this arti...

journal_title：Clinical transplantation

authors： Arbogast H,Hückelheim H,Schneeberger H,Illner WD,Tarabichi A,Fertmann J,Wimmer CD,Hillebrand GF,Mistry-Burchardi N,Thomae R,Acikgöz A,Land W

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Cardiac allograft vasculopathy (CAV) limits survival after heart transplantation (HTx). Between immunologic and non-immunologic factors, reactive oxygen species generation has been proposed as pathogenetic mechanism. This study was aimed at evaluating redox status in HTx recipients and verifying whether it c...

journal_title：Clinical transplantation

authors： De Chiara B,Bigi R,Campolo J,Parolini M,Turazza F,Masciocco G,Frigerio M,Fiorentini C,Parodi O

更新日期：2005-06-01 00:00:00

abstract：:We report of twins who underwent hematopoietic stem cell transplantation (HSCT) for neonatal acute leukemia. Hospitalized in the same room from the time the first one demonstrated respiratory symptoms, they both developed Pneumocystis jiroveci (formerly carinii) pneumonia (PCP) 2 wk apart. This observation suggests th...

journal_title：Clinical transplantation

authors： Resnick IB,Averbuch D,Aker M,Engelhard D

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:It is unclear whether sirolimus, a newer immunosuppressive agent, widely used in renal transplantation, affects male sex hormone levels or sexual function. METHODS:Sex hormone profiles in male renal transplant recipients were obtained and compared between a sirolimus-treated group and a group not on sirolim...

journal_title：Clinical transplantation

authors： Lee S,Coco M,Greenstein SM,Schechner RS,Tellis VA,Glicklich DG

更新日期：2005-04-01 00:00:00

abstract：:Urinary tract infections (UTIs) are the most common infectious complication following renal transplantation. Previous studies uniformly report that renal transplant recipients develop UTIs more often than the general population, but widely differ on how frequently UTIs occur after transplantation. These studies also d...

journal_title：Clinical transplantation

authors： Chuang P,Parikh CR,Langone A

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:There have been no published data on use of the the newer immunosuppressants tacrolimus and mycophenolate mofetil (MMF) in high immunological risk renal transplantation. We therefore undertook a prospective study to systematically assess outcomes using these agents as part of an aggressive immunosuppressive ...

journal_title：Clinical transplantation

authors： Zaltzman JS,Boucher A,Busque S,Halloran PF,Landsberg DN,McAlister VC,Russell D,Shoker A,Shapiro J,Tchervenkov JI,Ferguson R

更新日期：2005-02-01 00:00:00

abstract：:In Norway living kidney donors account for approximately 40% of all renal transplants. There is a shortage of information about how living kidney donors experience the donation process during the initial recovery from surgery. The aim of this study was to explore physical and psychosocial issues related to the experie...

journal_title：Clinical transplantation

authors： Andersen MH,Mathisen L,Øyen O,Wahl AK,Hanestad BR,Fosse E

更新日期：2005-02-01 00:00:00

abstract：INTRODUCTION:Recent immunosuppression with tacrolimus and mycophenolate mofetil has improved the results of renal transplantation. In this study, we analyzed the effect and safety of basiliximab as an induction therapy. MATERIAL AND METHODS:Forty-nine kidney recipients were given tacrolimus, mycophenolate mofetil and ...

journal_title：Clinical transplantation

authors： Miura M,Harada H,Fukuzawa N,Iwami D,Taniguchi A,Seki T,Togashi M,Ogawa Y,Satoh H,Hirano T

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The colloid-based University of Wisconsin (UW) preservation solution has been used extensively in clinical pancreas transplantation. Experimental studies support the use of the crystalloid-based histidine-tryptophan-ketoglutarate (HTK) preservation solution for this purpose. AIM:We report our initial experi...

journal_title：Clinical transplantation

authors： Potdar S,Malek S,Eghtesad B,Shapiro R,Basu A,Patel K,Broznick B,Fung J

更新日期：2004-12-01 00:00:00

abstract：:Chronic allograft nephropathy (CAN) is a major problem after renal transplantation and chronic inflammation can be one of its promoters. C-reactive protein (CRP) is an important marker of inflammation and atherosclerosis. We retrospectively analyzed the predictive role of serum CRP levels on the development of CAN and...

journal_title：Clinical transplantation

authors： Sezer S,Akcay A,Ozdemir FN,Kulah E,Arat Z,Haberal M

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:The pediatric end stage liver disease (PELD) score has been used widely to prioritize children awaiting cadaveric liver transplantation (LTx). To establish the objective parameter for optimal timing of living-related LTx (LRLTx), we have assessed our cases using the PELD score. METHODS:From 1997 to 2002, 24...

journal_title：Clinical transplantation

authors： Kimura T,Hasegawa T,Sasaki T,Shimizu Y,Mushiake S,Fukuzawa M,Okada A

更新日期：2004-10-01 00:00:00

abstract：:Flow cytometry crossmatch (FCXM) is a more sensitive technique than classical complement-dependent cytotoxicity (CDC) for the detection of donor-directed antibody before renal transplantation. Nevertheless, the role of FCXM in predicting long-term survival of kidney grafts is still unclear. The purpose of our study wa...

journal_title：Clinical transplantation

authors： Rebibou JM,Bittencourt MC,Saint-Hillier Y,Chabod J,Dupont I,Bittard H,Chalopin JM,Hervé P,Tiberghien P

更新日期：2004-10-01 00:00:00

abstract：:Sezer S, Ozdemir FN, Akcay A, Arat Z, Boyacioglu S, Haberal M. Renal transplantation offers a better survival in HCV-infected ESRD patients. Clin Transplant 2004 DOI: 10.1111/j.1399-0012.2004.00252. Abstract: The presence of hepatitis C virus (HCV) infection has been found to adversely affect the morbidity and mortali...

journal_title：Clinical transplantation

authors： Sezer S,Ozdemir FN,Akcay A,Arat Z,Boyacioglu S,Haberal M

更新日期：2004-10-01 00:00:00

abstract：:Subclinical acute rejection (SAR) occurs in about 30% of stable renal transplant patients and may be a risk factor for a poor allograft outcome. In the present study, the prevalence and clinical features of subclinical rejection, and the expression of immune activation markers in surveillance graft biopsies were asses...

journal_title：Clinical transplantation

authors： Veronese FV,Noronha IL,Manfro RC,Edelweiss MI,Goldberg J,Gonçalves LF

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:The clinical consequences of type 1 diabetes mellitus (IDDM) include diabetic triopathy: retinopathy, nephropathy, and neuropathy, as well as microangiopathy, accelerated atherosclerotic disease, and hypercoagulability. The etiology of the hypercoagulability is multifactorial, involving various clotting fact...

journal_title：Clinical transplantation

authors： Burke GW 3rd,Ciancio G,Figueiro J,Buigas R,Olson L,Roth D,Kupin W,Miller J

更新日期：2004-08-01 00:00:00